Controlled Rate Freezers

The Bio-Cool® is the most reliable, safest, and easiest to use controlled rate freezer for cryopreservation of human and animal embryos and biological tissue and cell lines. The Bio-Cool is the only controlled rate freezer that does not require expendable liquid nitrogen (LN2) and the associated pumping, re-filling, and storing of a high-pressure liquid. The Bio-Cool, conversely, simply plugs into a standard electrical outlet and quietly provides low temperature cooling to either -40ºC or -80ºC.

Unlike LN2 systems which surround samples with a cold vapor phase, the Bio-Cool immerses samples into a well-circulated, cold liquid bath. The circulating liquid allows more efficient heat transfer to the samples and maintains a more consistent temperature profile at all locations.

The Bio-Cool also has an easy-to-use programmable microprocessor controller with the ability to program and store up to eight different protocols, each with up to eight distinct segments specifying ramp rate, hold temperature, and hold time.

Elimination of LN2 handling and usage, better freezing results, simple straightforward operation, and world-class service support all make the Bio-Cool the controlled rate freezer of choice for most clinical, commercial, and research applications.

Controlled Rate Freezer
Simple, reliable, non-LN2 controlled rate freezing
Temperatures to -40ºC or -80ºC
Eliminates the use, handling, and storage of expendable high-pressure refrigerants (LN2)
Enables in-house cryopreservation capabilities to save time and money
FDA-registered medical device (Bio-Cool III model only
Bio-Cool Users and Applications
  In-vitro fertilization (IVF) facilities
    • Human embryo freezing
  University and Research Programs
    • Islet cells, tissue freezing
  Gene Banks
  Veterinary Clinics
    • Animal embryo freezing
  Transgenic embryo producer
    • Mouse embryo freezing
  Biotechnology companies